Healing of an extraction socket is an example of healing by
secondary intention.
Immediately after removal of tooth, the blood fills the
extraction site and both extrinsic and intrinsic pathways of clotting are
activated. This results in formation of fibrin meshwork that contains entrapped
RBCs and helps seal of the torn blood vessels and reduces the size of
extraction wound.
Clot organization begin 24-48 hours after extraction with:
-
Engorgement and dilatation
of blood vessels within PDL remnants
-
Followed by leukocytic migration and
-
Formation of a fibrin
layer.
1st Week:
-
The clot forms a
temporary scaffold upon which inflammatory cells migrate.
-
Epithelium at the wound
periphery grows over the surface of the organizing clot.
-
Osteoclasts accumulate
along the alveolar bone crest setting the stage for active crestal resorption.
-
Angiogenesis proceeds in
the remnants of the periodontal ligaments.
2nd Week:
-
The clot continues to
get organized through fibroplasia and new blood vessels that begin to penetrate
towards the center of the clot.
-
Trabeculae of osteoid
slowly extend into the clot from the alveolus, and osteoclastic resorption of
the cortical margin of the alveolar socket is more distinct.
3rd Week:
-
The extraction socket is
filled with granulation tissue and poorly calcified bone forms at the wound
perimeter.
-
The surface of the wound
is completely reepithelialized with minimal or no scar formation.
Active bone remodeling
by deposition and resorption continues for several more weeks.
Radiographic evidence of
bone formation does not become apparent until the sixth to eighth weeks following
tooth extraction. Due to the ongoing process of bone remodeling the final
healing product of the extraction site may not be discernible on radiographs
after 4 to 6 months.
REFERENCE: Peterson’s Principle Of Oral
And Maxillofacial Surgery, 2nd Edition
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